One of the most advertised features is its "Unhooked System Call" detection. Modern malware often uses a technique called SSDT Hooking (System Service Descriptor Table hooking) to hide its presence or redirect system queries.

The ability to map and monitor massive memory pools used by modern 64-bit applications.

Task Explorer x64 Exclusive: Unleashing Advanced Windows System Monitoring

You notice your web browser's memory usage is climbing into the gigabytes and never goes down. Using Task Explorer:

Search for specific file handles to see which process is locking a file.